Chemical Synthesis (Hepworth, Harry)

Chemical Synthesis of Nucleoside Analogues Chemical Synthesis of Nucleoside Analogues

The Dirty Harry Problem

Policing constantly places its practitioners in situations in which good ends can be achieved by dirty means. When the ends to be achieved are urgent and unquestionably good and only a dirty means will work to achieve them, the policeman faces a genuine moral dilemma. A genuine moral dilemma is a situation from which one cannot emerge innocent no matter what one does-employ a dirty means, emplo...

Harry Beal Torrey , Matthew

I t is now 16 years since Nowikoff (1908) accelerated the division rate of Paramecium by adding thyroid gland to his cultures. Later , Shumway (1914) reached the same conclusion after a series of more critical and painstaking experiments, and in the following year Budington and Harvey (1915) showed tha t thyroids from various vertebrates would produce similar results. Still later, Shumway (1917...

Chemical Synthesis of Oligonucleotides

It can fairly be said that synthetic oligonucleotides are the fuel that drives the engine of molecular biology. Nearly every technique in use today in molecular biology employs chemically synthesized DNAs or RNAs. This includes PCR, Real-Time PCR, DNA sequencing, site directed mutagenesis, single-nucleotide polymorphism (SNP) assays, microarrays, and the rapidly expanding world of small RNAs. U...

Ethics of Chemical Synthesis

Unlike other branches of science, the scientific products of synthetic chemistry are not only ideas but also new substances that change our material world, for the benefit or harm of living beings. This paper provides for the first time a systematical analysis of moral issues arising from chemical synthesis, based on concepts of responsibility and general morality. Topics include the questionin...